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Caspian J Intern Med 2017, 8(2): 99-103 Back to browse issues page
Comparative analysis of resected prostate weight in diabetic and non-diabetic benign prostatic hyperplasia patients
Emadouddin Moudi, Abazar Akbarzadeh-Pasha *
Associate Professor, Department of Urology, Shahid Beheshti hospital, Babol University of Medical Sciences, Babol, Iran , Aapasha812@yahoo.com
Abstract:   (6422 Views)

Background: Benign prostatic hyperplasia (BPH) is the most common benign tumor in men. The etiology of BPH is still unresolved and multiple systems are likely to be involved. The effects of diabetes on urinary system are a risk factor for BPH. We then assessed the effects of diabetes on the parameters related to BPH, especially weight and volume.

Methods: This study was conducted on patients with BPH who underwent surgery during 2010-2013. The patients’ demographic and clinical data including age, height, weight, history of diabetes, abdominal sonography, prostate-specific antigen(PSA), fasting blood sugar (FBS), triglyceride, and cholesterol, resected sample weight, and pathological diagnosis were extracted.

Results: The mean age of all 225 patients (35 (15.6%) diabetic patients and 190 (84.4%) non-diabetic patients) who entered the study was 71.5±8.7 years. The patients were divided in to 3 body mass index (BMI) groups: 48 (21.3%) were normal, 151 (67.1%) were overweight and 26 (11.6%) were obese. The mean weight of resected prostate was higher in diabetic patients (22.9±6.9 vs 21.7±14.3, P=0.02). The resected prostate weight had a significant relationship with BMI (P=0.001), prostate–specific antigen (PSA) level (P=0.001), and prostate volume sonography (P=0.001). No significant relationship was detected between resected prostate weight with age, FBS and triglyceride however, it is significant with cholesterol.

Conclusion: We concluded that diabetes has a role in the development and progression of BPH with effect on prostate weight and volume. As well, BMI is a risk factor in BPH progression.

Keywords: Diabetes, BPH, Prostate weight, PSA
Full-Text [PDF 174 kb]   (1257 Downloads)    
Type of Study: Original Article | Subject: Internal
Received: 2016/10/2 | Accepted: 2016/11/29 | Published: 2017/02/20
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Moudi E, Akbarzadeh-Pasha A. Comparative analysis of resected prostate weight in diabetic and non-diabetic benign prostatic hyperplasia patients . Caspian J Intern Med. 2017; 8 (2) :99-103
URL: http://caspjim.com/article-1-879-en.html


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Volume 8, Issue 2 (2-2017) Back to browse issues page
Caspian Journal of Internal Medicine
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