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Comparison between Myocardial Infarction with Non Obstructive Coronaries (MINOCA) and Myocardial Infarct Patients with Coronary Artery Disease (MI-CAD): a single-center retrospective cohort study
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Abbas Andishmand    , Mahmood Emami Meybodi , Seyedeh Mahdieh Namayandeh , Hamid Reza Mohammadi , Mojtaba Andishmand , Mohammadali Zarbakhsh , Marzieh Azimizade |
| Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. , mohammad_zarbakhsh@yahoo.com |
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Abstract: (784 Views) |
Background: The coronary angiography results in a group of patients with myocardial infarction (MI) are normal or near-normal; which is diagnosed as myocardial infarction with non-obstructive coronary arteries (MINOCA). This study aimed to compare the mortality rate and risk factors between MINOCA and myocardial infarction with obstructive coronary artery (MI-CAD).
Methods: This retrospective cohort study was conducted from January 1, 2018, to December 31, 2019. A total of 679 patients admitted to Afshar Hospital in Yazd with a diagnosis of ST-elevation myocardial infarction (STEMI) from 2018-2019 who underwent primary Percutaneous Coronary Intervention (PCI) were enrolled in the study. Demographic, and clinical variables, ECG finding and one-year mortality, were extracted using MI registry data from the Yazd Cardiac Research Center.
Results: The estimated frequency of MINOCA was 4.6%. Patients with MINOCA (
47.14±6.2) were younger than patients with MI-CAD (57.61±9.1) (P <0.0001). MINOCA patients (47.4±9.47) had a considerably greater left ventricular ejection fraction (LVEF) than MI-CAD patients (43.5±6.8) (P =0.018). The majority site of MI in MINOCA patients was located in the non-anterior wall (p <0.0001). A comparison of MINOCA and MI-CAD patients' one-year mortality revealed no significant difference (P =0.07).
Conclusion: The prevalence of patients with MINOCA in Yazd was similar to other communities. Although these patients probably do not have a better prognosis, despite being younger and having better LV systolic function and lower CAD risk factors.
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| Keywords: MINOCA, MI-CAD, STEMI |
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Full-Text [PDF 530 kb]
(322 Downloads)
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Type of Study: Original Article |
Subject:
Cardiology
Received: 2022/12/12 | Accepted: 2023/03/28 | Published: 2024/01/19
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