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:: Volume 4, Issue 1 (1-2013) ::
Caspian J Intern Med 2013, 4(1): 574-576 Back to browse issues page
Full blood count pattern of pre-chemotherapy breast cancer patients in Lagos, Nigeria
Akinsegun Akinbami *, Abiodun Popoola, Adewumi Adediran, Adedoyin Dosunmu, Olajumoke Oshinaike, Philip Adebola, Sarah Ajibola
Abstract:   (8052 Views)
Background: Full blood count has been shown to predict disease severity and mortality risk in cancer patients. This study aimed to highlight the degree of derangements of full blood count parameters and provide mean values in pre-chemotherapy breast cancer patients compared with apparently normal control subjects.
Methods: This was an unmatched case-control study among breast cancer patients attending Oncology clinic of Lagos State University Teaching Hospital, Ikeja and the nurses of the institution as control. A total of 4.5 mls of blood was collected from each participant into EDTA bottle for full blood count analysis, done on the same day of collection.
Results: A total of 100 histologically diagnosed, consenting, pre-chemotherapy patients of the clinic (cases) and 50 nurses of the institution as controls were studied. Anemia was found in 58%, 43% and 20% of cases compared with 38%, 36% and 2% of controls using PCV< 36%, 30-36% and 30%, respectively. The mean MCV, MCH, MCHC (82.62±7.48 fl, 26.01±2.78 pg, 30.73±4.06 g/l respectively) of cases were lower than the controls (85.36±5.74 fl, 27.24±1.90 pg, 31.81±0.8 g/l, respectively and RDW of cases (15.61±3.53) was higher than the control (14.24±0.75). The mean WBC counts, neutrophil and lymphocyte percentages of cases (6.96±7.22, 54.75±13.1% and 38.19±12.70%, respectively) were higher than the controls (5.47±1.57, 44.39±8.78% and 8.82±15.97%, respectively). The mean platelet count of cases 291.51±103.38 was also higher than the controls (222.82±57.62).
Conclusion: Breast cancer patients presented with deranged full blood count pattern, consequent to the disease compared with the controls.
Keywords: Full blood count, Pre-chemotherapy, Breast cancer
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Type of Study: Original Article | Subject: Infectious Diseases
Received: 2014/01/15 | Accepted: 2014/01/15 | Published: 2014/01/15
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Akinbami A, Popoola A, Adediran A, Dosunmu A, Oshinaike O, Adebola P et al . Full blood count pattern of pre-chemotherapy breast cancer patients in Lagos, Nigeria. Caspian J Intern Med 2013; 4 (1) :574-576
URL: http://caspjim.com/article-1-187-en.html

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Volume 4, Issue 1 (1-2013) Back to browse issues page
Caspian Journal of Internal Medicine
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