[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 13 - Covid 19 Supplement 2 ::
Caspian J Intern Med 2022, 13 - Covid 19 Supplement 2: 193-198 Back to browse issues page
COVID-19 and renal involvement in children: a retrospective study
Hadi Sorkhi , Mohamadreza Esmaeilidooki , Maryam Nikpour * , Mohsen Mohammadi , Ali Mohammadpour-Mir5 , Masood Kiani , Sanaz Mehrabani , Sahar Sadr Moharerpour , Morteza Alijanpour , Kazem Babazadeh , Hassan Mahmoodi-Nesheli , Mohamadreza Tabatabaie , Ahmad Tamaddoni , Mohammadreza Salehiomran , Paiam Payandeh , Iraj Mohammadzadeh , Sareh Hosseinpour
Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran , maryamnikpour19@yahoo.com
Abstract:   (1314 Views)
Background: The New coronavirus (SARS COV-2) can cause acute respiratory disease and also multiorgan dysfunction. There is insufficient data about kidney involvement in children. So, this study was done on children with COVID-19 to evaluate nephrological involvement.
Methods: All children with confirmed or suspected COVID-19 who were admitted in Children Hospital .were enrolled. They were admitted in hospital from March 2020 to July 2020. Serum Blood Urea Nitrogen (BUN), creatinine, sodium, potassium, calcium and urinalysis were evaluated. Also, glomerular filtration rate (GFR) was calculated by Schertz's formula. All patients were evaluated by chest x-ray and/or computerized tomography scanning (CTS). The data were analyzed by SPSS software and P value less than 0.05 was determined as significant.
Results: Forty-seven children with confirmed or suspected COVID-19 were enrolled to this study. At admission, 23.4% and 27.7% of children with COVID-19 had abnormal increase in serum BUN and creatinine, respectively. Also 78.8% and 25.5% of children had GFR less than 90 and 60 ml/min /1.732, respectively. Additionally, 13/47 (27.7%) of children had abnormal urine analysis (microscopic hematuria and/or proteinuria). There wasn’t a significant relationship between pulmonary lesions and abnormal reduction of GFR (P<0/05).
Conclusion: In the study, the risk of AKI (acute kidney injury) and decrease of GFR and also abnormal urinalysis is high in children with COVID-19. So, more attention for detection of kidney involvement is necessary and more conservative management for prevention of AKI and decrease of GFR are recommended.

Keywords: COVID-19, renal failure, pediatrics, kidney involvement 
Full-Text [PDF 319 kb]   (436 Downloads)    
Type of Study: Original Article | Subject: Infectious Diseases
Received: 2020/09/13 | Accepted: 2020/12/14 | Published: 2022/04/6
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sorkhi H, esmaeilidooki M, Nikpour M, Mohammadi M, Mohammadpour-Mir5 A, Kiani M, et al et al . COVID-19 and renal involvement in children: a retrospective study. Caspian J Intern Med 2022; 13 :193-198
URL: http://caspjim.com/article-1-2499-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 13 - Covid 19 Supplement 2 Back to browse issues page
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4570