[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Impact Factor 2022: 1.4
Cite Score 2022: 2.1
SJR 2022: 0.347
SNIP 2022: 0.545
Publication Charge
►Publication Fee
In Press
 In Press Articles
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
:: Volume 15, Issue 1 (Winter 2024) ::
Caspian J Intern Med 2024, 15(1): 87-95 Back to browse issues page
Predictive value of Body Mass Index (BMI) and Determination of optimum Cut-off Point in the diagnosis of endometrial hyperplasia in Pre-menopausal women with abnormal uterine Bleeding
Sara Alizadeh Garna , Shahla Yazdani , Hadis Mosavi , Mohammad Ranaei , Karimollah Hajian-Tilaki , Zinatossadat Bouzari
Babol uiniverstiy of Medical scinces , z_b412003@yahoo.com
Abstract:   (275 Views)
Background: The suitable BMI cut-off point in persons with endometrial cancer or hyperplasia with abnormal uterine bleeding was investigated in this study.
Methods: This case-control research was conducted on 1470 women with abnormal uterine bleeding in Ayatollah Rouhani Hospital,Babol between 2010 and 2012, with 312 participants included in the study. In terms of uterine biopsy results, patients were split into six groups: simple hyperplasia without atypia, simple hyperplasia with atypia, complicated hyperplasia with atypia, complex hyperplasia without atypia, endometrial cancer, and normal persons.
Results: The mean age and BMI of patients in these three groups were not significantly different (P equal to 0.081 and 0.435, respectively). The kind of disease exhibited a strong relationship with menstruation (P 0.001). The body mass index (BMI) values ​​did not have significant levels under the curve to determine the appropriate cut-off point in the diagnosis of hyperplasia plus endometrial cancer and endometrial cancer alone (P 0.380 and 0.124, respectively) and hyperplasia alone (P = 0.920). Based on logistic regression, age 50 years and older and irregular menstruation were significant with OR equal to 2.36 and 2.09 (P = 0.011) and HTN with OR equal to 0.44 (P = 0.026), respectively.
Conclusion: BMI has little predictive value in the detection of endometrial cancer or hyperplasia, according to the findings, and other diagnostic and screening modalities should be utilized instead. The findings backed up the theory that old age and irregular menstruation are linked to an increased risk of endometrial cancer.

Keywords: Abnormal Uterine Bleeding, Endometrial Cancer, Endometrial Hyperplasia, Body Mass Index, Infertility.
Full-Text [PDF 818 kb]   (126 Downloads)    
Type of Study: Original Article | Subject: Obstetrics & Gynicology
Received: 2022/05/14 | Accepted: 2023/03/11 | Published: 2024/01/19
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Alizadeh Garna S, Yazdani S, Mosavi H, ranaei M, Hajian-Tilaki K, Bouzari Z. Predictive value of Body Mass Index (BMI) and Determination of optimum Cut-off Point in the diagnosis of endometrial hyperplasia in Pre-menopausal women with abnormal uterine Bleeding. Caspian J Intern Med 2024; 15 (1) :87-95
URL: http://caspjim.com/article-1-3486-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 15, Issue 1 (Winter 2024) Back to browse issues page
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.05 seconds with 40 queries by YEKTAWEB 4642