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:: Volume 15, Issue 1 (Winter 2024) ::
Caspian J Intern Med 2024, 15(1): 124-131 Back to browse issues page
Mediatory Role of the Serum Mineral Level and Discharge Disability of Stroke Survivors
Soraya Khafri , Alijan Ahmadi Ahangar , Payam Saadat , Shayan Alijanpour , Mansor Babaei , Mohammadali Bayani , Alireza Firouzjahi , Farshad Fadaee Jouybari , Sepideh Hosseini Shirvani , Zahra Frajzadeh , Nafisseh Ezamie
Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran , Sepanta1968@yahoo.com
Abstract:   (257 Views)
Background: Possible association between minerals contributing and mortality related to stroke were seen, but prospective data on the relation of vitamin D, magnesium and calcium serum levels with stroke were inconsistent. Consideration about the potential health effects of minerals and nutrients, the current study was conducted.
Methods: This analytical cross-sectional study was conducted on 216 stroke survivors who were referred to the Ayatollah Rouhani Hospital of Babol, Iran. Demographic characteristics, clinical variables, and serum mineral levels were completed in the checklist. Admit score and discharge scale of these patients were determined according to the National Institute of Health Stroke Scale. A path model was constructed to explore the interrelationship between variables and to verify the relationship between variables and disability discharges.
Results: Of 216 stroke patients, 185 (85.6%) cases were ischemic. The discharge status of 29 (12.9%) cases were severe or expired. The patients with moderate and severe admit scores, hemorrhagic stroke type, diabetes mellitus, hypertension and live in the village significantly had a poor discharge disability scale (all of p<0.05). Of all direct paths, Mg (β=-2.85), and among indirect paths, calcium(β=-3.59) had the highest effect on the discharge scale. Only mg had affected the discharge scale through direct and indirect (β=-2.45) paths and had the greatest reverse effect on the discharge scale (β=-5.30; totally).
Conclusion: Hypomagnesemia and hypocalcemia play a mediatory role in poor outcomes. Especially, hypomagnesemia was the direct parameter for poor outcomes. The independent role of each mineral in this issue is difficult to define and suggested for future study.

Keywords: magnesium, calcium, vita D, ischemic stroke, stroke
Full-Text [PDF 564 kb]   (188 Downloads)    
Type of Study: Original Article | Subject: Neurology
Received: 2022/12/18 | Accepted: 2024/01/19 | Published: 2024/01/19
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Khafri S, Ahmadi Ahangar A, Saadat P, Alijanpour S, Babaei M, Bayani M, et al . Mediatory Role of the Serum Mineral Level and Discharge Disability of Stroke Survivors. Caspian J Intern Med 2024; 15 (1) :124-131
URL: http://caspjim.com/article-1-3798-en.html

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Volume 15, Issue 1 (Winter 2024) Back to browse issues page
Caspian Journal of Internal Medicine
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