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:: Volume 1, Issue 3 (1-2010) ::
Caspian J Intern Med 2010, 1(3): 111-114 Back to browse issues page
Severe muscle weakness during treatment with pegylated interferon alfa for chronic hepatitis C virus infection A rare complication
Maryam Mobini *
Abstract:   (7644 Views)
Background: Interferons (IFNs) are common therapeutics for several diseases such as viral hepatitis, multiple sclerosis and malignancy. A variety of autoimmune related side effects have been observed during IFN therapy. Rare cases of myopathy, polymyositis or dermatomyositis have been reported during therapy with high doses of IFNα.
Case Presentation: In this report, we describe a case with severe muscle weakness but near normal muscles' enzymes during treatment of chronic hepatic C infection with pegylated IFN α 2a in a patient with major beta thalassemia
Conclusion: This report suggests that severe weakness with normal musclesα enzymes may occur during IFN therapy.
Keywords: Interferon, Muscle Weakness, Pegylated Interferon, Myopathy
Full-Text [PDF 128 kb]   (2338 Downloads)    
Type of Study: Original Article | Subject: Infectious Diseases
Received: 2014/01/14 | Accepted: 2014/01/14 | Published: 2014/01/14
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Mobini M. Severe muscle weakness during treatment with pegylated interferon alfa for chronic hepatitis C virus infection A rare complication. Caspian J Intern Med. 2010; 1 (3) :111-114
URL: http://caspjim.com/article-1-85-en.html


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Volume 1, Issue 3 (1-2010) Back to browse issues page
Caspian Journal of Internal Medicine
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